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Wei Chen Selected Research

Oligodeoxyribonucleotides

1/2019An effective dendritic cell-based vaccine containing glioma stem-like cell lysate and CpG adjuvant for an orthotopic mouse model of glioma.
4/2018Toll-like receptor 9 activation by CpG oligodeoxynucleotide 7909 enhances the radiosensitivity of A549 lung cancer cells via the p53 signaling pathway.
1/2017Heterogeneity of Toll-like receptor 9 signaling in B cell malignancies and its potential therapeutic application.
1/2015The effect of ataxia-telangiectasia mutated kinase-dependent hyperphosphorylation of checkpoint kinase-2 on oligodeoxynucleotide 7909 containing CpG motifs-enhanced sensitivity to X-rays in human lung adenocarcinoma A549 cells.
9/2013CpG-ODN 7909 increases radiation sensitivity of radiation-resistant human lung adenocarcinoma cell line by overexpression of Toll-like receptor 9.
1/2013Dose-effect relationship of CpG oligodeoxyribonucleotide 1826 in murine Lewis lung cancer treated with irradiation.
1/2012Impact of CHK2-small interfering RNA on CpG ODN7909-enhanced radiosensitivity in lung cancer A549 cells.
4/2011CpG oligodeoxynucleotide 1826 enhances the Lewis lung cancer response to radiotherapy in murine tumor.
10/2010Superior efficacy of tumor cell vaccines grown in physiologic oxygen.
6/2010Toll-like receptor 9 signaling by CpG-B oligodeoxynucleotides induces an apoptotic pathway in human chronic lymphocytic leukemia B cells.
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Wei Chen Research Topics

Disease

977Neoplasms (Cancer)
12/2022 - 03/2002
251Inflammation (Inflammations)
08/2022 - 01/2004
165Neoplasm Metastasis (Metastasis)
06/2022 - 03/2005
160Infections
11/2022 - 04/2003
123Breast Neoplasms (Breast Cancer)
05/2022 - 11/2002
119Hepatocellular Carcinoma (Hepatoma)
10/2022 - 08/2003
90Colorectal Neoplasms (Colorectal Cancer)
07/2022 - 06/2002
87Carcinoma (Carcinomatosis)
06/2022 - 03/2002
81Carcinogenesis
05/2022 - 10/2003
78Lung Neoplasms (Lung Cancer)
06/2022 - 04/2006
77Hypertension (High Blood Pressure)
03/2022 - 03/2002
76Insulin Resistance
09/2022 - 05/2003
71Fibrosis (Cirrhosis)
12/2022 - 03/2002
71Obesity
11/2022 - 07/2002
68Hypoxia (Hypoxemia)
07/2022 - 01/2004
67Urinary Bladder Neoplasms (Bladder Cancer)
02/2022 - 04/2003
63Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
05/2022 - 12/2004
62Wounds and Injuries (Trauma)
08/2022 - 01/2002
59COVID-19
08/2022 - 01/2020
58Stomach Neoplasms (Stomach Cancer)
02/2022 - 03/2003
56Type 2 Diabetes Mellitus (MODY)
01/2022 - 03/2003
55Body Weight (Weight, Body)
11/2022 - 02/2005
55Prostatic Neoplasms (Prostate Cancer)
05/2022 - 01/2003
53Glioma (Gliomas)
01/2022 - 12/2004
52Pain (Aches)
11/2022 - 07/2007
50Ovarian Neoplasms (Ovarian Cancer)
01/2022 - 01/2004
47Pancreatic Neoplasms (Pancreatic Cancer)
12/2021 - 03/2008
41Alzheimer Disease (Alzheimer's Disease)
02/2022 - 08/2006
41Ischemia
01/2022 - 01/2002
40Renal Cell Carcinoma (Grawitz Tumor)
01/2022 - 06/2008
39Stroke (Strokes)
11/2022 - 08/2003
39Colitis
07/2022 - 06/2007
39Metabolic Syndrome (Dysmetabolic Syndrome X)
09/2021 - 06/2005
38Myocardial Infarction
02/2022 - 06/2004
37Asthma (Bronchial Asthma)
04/2022 - 03/2009
35Sepsis (Septicemia)
06/2022 - 11/2006
35Colonic Neoplasms (Colon Cancer)
02/2022 - 05/2004
35Adenocarcinoma
01/2022 - 10/2007
33Hemorrhage
09/2022 - 01/2003
33Pneumonia (Pneumonitis)
05/2022 - 03/2010
33Cardiovascular Diseases (Cardiovascular Disease)
03/2022 - 04/2005
31Parkinson Disease (Parkinson's Disease)
07/2022 - 11/2007
31Atherosclerosis
04/2022 - 03/2004
31Necrosis
01/2022 - 03/2005
29Leukemia
06/2022 - 03/2002
28Liver Cirrhosis (Hepatic Cirrhosis)
06/2022 - 05/2006
28Infarction (Infarctions)
01/2022 - 03/2010

Drug/Important Bio-Agent (IBA)

320Proteins (Proteins, Gene)FDA Link
10/2022 - 03/2002
197Biomarkers (Surrogate Marker)IBA
07/2022 - 06/2005
176Pharmaceutical PreparationsIBA
05/2022 - 08/2004
131MicroRNAs (MicroRNA)IBA
07/2022 - 03/2007
127Biological ProductsIBA
07/2022 - 04/2003
119CytokinesIBA
07/2022 - 11/2004
108Messenger RNA (mRNA)IBA
07/2022 - 01/2004
95Long Noncoding RNAIBA
09/2022 - 03/2012
92Glucose (Dextrose)FDA LinkGeneric
06/2022 - 07/2002
79DNA (Deoxyribonucleic Acid)IBA
04/2022 - 04/2002
70VaccinesIBA
08/2022 - 04/2002
65RNA (Ribonucleic Acid)IBA
09/2022 - 01/2004
64Small Interfering RNA (siRNA)IBA
07/2022 - 02/2008
59EnzymesIBA
06/2022 - 11/2004
58Therapeutic UsesIBA
06/2022 - 07/2003
56Interleukin-6 (Interleukin 6)IBA
06/2022 - 11/2004
54LipidsIBA
09/2022 - 11/2006
53Cisplatin (Platino)FDA LinkGeneric
01/2022 - 11/2008
51Insulin (Novolin)FDA Link
01/2022 - 05/2003
48AntigensIBA
03/2022 - 03/2002
47Reactive Oxygen Species (Oxygen Radicals)IBA
07/2022 - 02/2009
47Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
08/2021 - 03/2002
44Triglycerides (Triacylglycerol)IBA
05/2022 - 07/2003
43CollagenIBA
01/2022 - 08/2003
41C-Reactive ProteinIBA
03/2022 - 06/2006
41Peptides (Polypeptides)IBA
01/2022 - 09/2004
40Indicators and Reagents (Reagents)IBA
06/2022 - 02/2005
40Transcription Factors (Transcription Factor)IBA
01/2022 - 05/2006
39Anti-Bacterial Agents (Antibiotics)IBA
01/2022 - 02/2003
39Doxorubicin (Adriamycin)FDA LinkGeneric
01/2022 - 02/2008
33CholesterolIBA
03/2022 - 06/2005
32InflammasomesIBA
06/2022 - 01/2013
32CateninsIBA
01/2022 - 10/2010
31LigandsIBA
12/2022 - 04/2003
31AntioxidantsIBA
07/2022 - 05/2008
30CreatinineIBA
02/2022 - 08/2007
30Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
12/2021 - 07/2003
29Oxygen (Dioxygen)IBA
11/2022 - 08/2006
29Blood Glucose (Blood Sugar)IBA
08/2022 - 04/2005
29Phosphotransferases (Kinase)IBA
06/2022 - 11/2003
29AlbuminsIBA
04/2022 - 11/2006
29AntibodiesIBA
02/2022 - 09/2004
29Cadherins (E-Cadherin)IBA
01/2022 - 10/2010
29HDL CholesterolIBA
01/2021 - 07/2003
28LipopolysaccharidesIBA
06/2022 - 12/2002

Therapy/Procedure

471Therapeutics
12/2022 - 03/2002
161Drug Therapy (Chemotherapy)
03/2022 - 12/2004
57Radiotherapy
05/2022 - 12/2004
48Immunotherapy
06/2022 - 09/2004
34Photochemotherapy (Photodynamic Therapy)
01/2022 - 04/2006
33Length of Stay
05/2022 - 11/2006
33Lasers (Laser)
09/2020 - 07/2007
32Transplantation
01/2022 - 12/2004